A new hope for sufferers of Attention-Deficit Hyperactivity Disorder (ADHD)
Attention-deficit hyperactivity disorder (ADHD) is the most common developmental disorder that is associated with environmental and genetic factors. Neurobiological evidence suggests that fronto-striatum-cerebellum circuit abnormalities, mainly in the right hemisphere, are responsible for most of the disturbed sensorimotor integration; dopamine seems to be the main neurochemical alteration underlying these morphological abnormalities.
Different conventional treatments have been employed on ADHD; however, repetitive transcranial magnetic stimulation (rTMS), a new and useful option for the clinical/research investigation of several neuropsychiatric disorders involving dopamine circuits, has yet to be considered as a therapeutic tool and possible drug-free option for ADHD.
Here the authors explore the available evidence that makes this tool a rational therapeutic possibility for patients with ADHD, calling attention to safety issues, while highlighting the potentials of such an approach and the new hope it may bring for patients, parents, researchers and clinicians. The authors advocate carefully conducted clinical trials to investigate efficacy, safety, cost-effectiveness and clinical utility of rTMS for ADHD patients in comparison to both placebo and standard treatments.Attention-deficit hyperactivity disorder (ADHD) is the most common developmental disorder affecting at least 5% of school-aged children, with boys more frequently affected than girls.
It persists into adulthood in up to 60% of the cases. It is characterized by inattention, impulsiveness and hyperactivity that impair normal daily life function, especially at home and school. The long-term consequences of childhood ADHD include lower educational and vocational outcomes as well as an increased risk for antisocial behavioral disorders and drug abuse in adulthood, among other psychopathologies.
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